Next-generation diagnostics: virus capture facilitates a sensitive viral diagnosis for epizootic and zoonotic pathogens including SARS-CoV-2

Abstract Background The detection of pathogens in clinical and environmental samples using high-throughput sequencing (HTS) is often hampered by large amounts of background information, which is especially true for viruses with small genomes. Enormous sequencing depth can be necessary to compile suf...

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Bibliographic Details
Main Authors: Claudia Wylezich, Sten Calvelage, Kore Schlottau, Ute Ziegler, Anne Pohlmann, Dirk Höper, Martin Beer
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-020-00973-z