The NF-κB Activating Pathways in Multiple Myeloma

The NF-κB Activating Pathways in Multiple Myeloma

Multiple myeloma(MM), an incurable plasma cell cancer, represents the second most prevalent hematological malignancy. Deregulated activity of the nuclear factor kappaB (NF-κB) family of transcription factors has been implicated in the pathogenesis of multiple myeloma. Tumor microenvironmen...

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Bibliographic Details
Main Authors: Payel Roy, Uday Aditya Sarkar, Soumen Basak
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Biomedicines
Subjects:
NF-κB
multiple myeloma
canonical
non-canonical
mutations
microenvironment
cytokines
crosstalk
gene-expressions
Online Access:http://www.mdpi.com/2227-9059/6/2/59

Internet

http://www.mdpi.com/2227-9059/6/2/59

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