Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

Obstructive sleep apnea (OSA) results from episodes of airway collapse and intermittent hypoxia (IH) and is associated with a host of health complications. Although the lung is the first organ to sense changes in oxygen levels, little is known about the consequences of IH to the lung hypoxia-inducib...

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Bibliographic Details
Main Authors: Gang Wu, Yin Yeng Lee, Evelyn M Gulla, Andrew Potter, Joseph Kitzmiller, Marc D Ruben, Nathan Salomonis, Jeffery A Whitsett, Lauren J Francey, John B Hogenesch, David F Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
obstructive sleep apnea
single cell sequencing
intermittent hypoxia
lung
RNA sequencing
Online Access:https://elifesciences.org/articles/63003

Internet

https://elifesciences.org/articles/63003

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