Viral status, immune microenvironment and immunological response to checkpoint inhibitors in hepatocellular carcinoma

Background and aimsImmune checkpoint inhibitors (ICIs) targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway have clinical activity in hepatocellular carcinoma (HCC), but only a subset of patients respond to these therapies, highlighting a need for novel biom...

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Bibliographic Details
Main Authors: Su Jin Lim, Stephanie Xavier, Marcelo B Sztein, Elana J Fertig
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000394.full