Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors

Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) belong to the largest class of drug targets. Approximately half of the members of the human GPCR superfamily are chemosensory receptors, including odorant receptors (ORs), trace amine-associated receptors (TAARs), bitter taste receptors (TAS2Rs), sweet and umami t...

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Bibliographic Details
Main Authors: Antonella Di Pizio, Maik Behrens, Dietmar Krautwurst
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
smell
taste
flavour molecules
drugs
chemosensory receptors
ecnomotopic expression
Online Access:https://www.mdpi.com/1422-0067/20/6/1402

Internet

https://www.mdpi.com/1422-0067/20/6/1402

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