The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in <i>Streptomyces</i>

Microbial natural product drug discovery and development has entered a new era, driven by microbial genomics and synthetic biology. Genome sequencing has revealed the vast potential to produce valuable secondary metabolites in bacteria and fungi. However, many of the biosynthetic gene clusters are s...

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Bibliographic Details
Main Authors: Saibin Zhu, Yanwen Duan, Yong Huang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/8/3/133