Remission of Severe, Relapsed, and Refractory TTP after Multiple Cycles of Bortezomib
Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by autoantibodies against a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13). Uncleaved von Willebrand factor (VWF) multimers accumulate and bind to platelets which causes spontaneous microt...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2017/9681832 |