Remission of Severe, Relapsed, and Refractory TTP after Multiple Cycles of Bortezomib

Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by autoantibodies against a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13). Uncleaved von Willebrand factor (VWF) multimers accumulate and bind to platelets which causes spontaneous microt...

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Bibliographic Details
Main Authors: Manu R. Pandey, Pankit Vachhani, Evelena P. Ontiveros
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/9681832