Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition

Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition

Uveal melanoma (UM) is a rare tumor of the eye that leads to deadly metastases in about half of the patients. ADAM10 correlates with c-Met expression in UM and high levels of both molecules are related to the development of metastases. MiR122 and miR144 modulate <i>ADAM10</i> and <i&g...

Full description

Bibliographic Details
Main Authors: Adriana Amaro, Michela Croce, Silvano Ferrini, Gaia Barisione, Marina Gualco, Patrizia Perri, Ulrich Pfeffer, Martine J. Jager, Sarah E. Coupland, Carlo Mosci, Gilberto Filaci, Marina Fabbi, Paola Queirolo, Rosaria Gangemi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
uveal melanoma
miRNA
ADAM10
c-Met
onco-suppressor
Online Access:https://www.mdpi.com/2072-6694/12/6/1468

Internet

https://www.mdpi.com/2072-6694/12/6/1468

Similar Items