Osteoarticular Changes in Acromegaly

Acromegaly is caused by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-I (IGF-1) due to pituitary tumor. Other causes, such as increased growth-hormone releasing hormone (GHRH) production, ectopic GHRH production, and ectopic GH secretion, are rare. Growth hormo...

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Bibliographic Details
Main Authors: Zdenko Killinger, Martin Kužma, Lenka Sterančáková, Juraj Payer
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/839282