Alternative splicing of the RAGE cytoplasmic domain regulates cell signaling and function.

The Receptor for Advanced Glycation End-products (RAGE) is a multi-ligand receptor present on most cell types. Upregulation of RAGE is seen in a number of pathological states including, inflammatory and vascular disease, dementia, diabetes and various cancers. We previously demonstrated that alterna...

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Bibliographic Details
Main Authors: Joel Jules, Dony Maiguel, Barry I Hudson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832623?pdf=render