A Novel Polyamine-Targeted Therapy for BRAF Mutant Melanoma Tumors
Mutant serine/threonine protein kinase B-Raf (BRAF) protein is expressed in over half of all melanoma tumors. Although BRAF inhibitors (BRAFi) elicit rapid anti-tumor responses in the majority of patients with mutant BRAF melanoma, the tumors inevitably relapse after a short time. We hypothesized th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-01-01
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| Series: | Medical Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3271/6/1/3 |