Tumor M2-PK: A novel urine marker of bladder cancer.

Tumor M2-PK: A novel urine marker of bladder cancer.

<h4>Purpose</h4>Bladder cancer is a "Warburg-like" tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in particular PKM2 dime...

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Bibliographic Details
Main Authors: Weiya Liu, Benjamin L Woolbright, Karim Pirani, Ryan Didde, Erika Abbott, Gaurav Kaushik, Paige Martin, Jill Hamilton-Reeves, John A Taylor, Jeffrey M Holzbeierlein, Shrikant Anant, Eugene K Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218737

Internet

https://doi.org/10.1371/journal.pone.0218737

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