Hemoglobin Genotypes Modulate Inflammatory Response to Plasmodium Infection

In 2018, 228 million cases and 405,000 malaria-associated deaths were reported worldwide with a majority being in Africa. A wide range of factors, including parasitemia, host immunity, inflammatory responses to infection, and host hemoglobin genotype, mediate the severity of malaria. Among the hemog...

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Bibliographic Details
Main Authors: Keri Oxendine Harp, Felix Botchway, Yvonne Dei-Adomakoh, Michael D. Wilson, Joshua L. Hood, Andrew A. Adjei, Jonathan K. Stiles, Adel Driss
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.593546/full