Citalopram Ameliorates Impairments in Spatial Memory and Synaptic Plasticity in Female 3xTgAD Mice

Alzheimer’s disease (AD) is the primary cause of dementia. There is no effective treatment. Amyloid-β peptide (Aβ) plays an important role in the pathogenesis and thus strategies suppressing Aβ production and accumulation seem promising. Citalopram is an antidepressant drug and can decrease Aβ produ...

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Bibliographic Details
Main Authors: Zhang Wei, Guo Junhong, Niu Xiaoyuan, Wang Jie, Wang Zhaojun, Wu Meina, Yang Wei, Zhang Jun, Qi Jinshun
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/1238687