Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis.

Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis.

Recently, heightened systemic translocation of microbial products was found in persons with chronic HIV infection and this was linked to immune activation and CD4(+) T cell homeostasis.We examined here the effects of microbial Toll-like receptor (TLR) ligands on T cell activation in vitro.We show th...

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Bibliographic Details
Main Authors: Nicholas Funderburg, Angel A Luciano, Wei Jiang, Benigno Rodriguez, Scott F Sieg, Michael M Lederman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2271052?pdf=render

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http://europepmc.org/articles/PMC2271052?pdf=render

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