Synthetic Nucleotides as Probes of DNA Polymerase Specificity

The genetic code is continuously expanding with new nucleobases designed to suit specific research needs. These synthetic nucleotides are used to study DNA polymerase dynamics and specificity and may even inhibit DNA polymerase activity. The availability of an increasing chemical diversity of nucleo...

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Bibliographic Details
Main Authors: Jason M. Walsh, Penny J. Beuning
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2012/530963