Comparisons of plasma aldosterone and renin data between an automated chemiluminescent immunoanalyzer and conventional radioimmunoassays in the screening and diagnosis of primary aldosteronism.

Determining values of plasma renin activity (PRA) or plasma active renin concentration (ARC), plasma aldosterone concentration (PAC), and aldosterone-to-renin ratio (ARR) is essential to diagnose primary aldosteronism (PA), but it takes several days with conventional radioimmunoassays (RIAs). Chemil...

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Main Authors: Naohisa Tamura, Erika Watanabe, Rumi Shirakawa, Eiji Nakatani, Kanako Yamada, Hiroshi Hatakeyama, Mizuki Torii-Hanakita, Chika Kyo, Rieko Kosugi, Tatsuo Ogawa, Masato Kotani, Takeshi Usui, Tatsuhide Inoue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253807