Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia.

Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia.

Pulmonary surfactant protein D (SP-D) is a host defence lectin of the innate immune system that enhances clearance of pathogens and modulates inflammatory responses. Recently it has been found that systemic SP-D is associated with metabolic disturbances and that SP-D deficient mice are mildly obese....

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Bibliographic Details
Main Authors: Jacob V Stidsen, Reza Khorooshi, Martin K U Rahbek, Katrine L Kirketerp-Møller, Pernille B L Hansen, Peter Bie, Karin Kejling, Susanne Mandrup, Samuel Hawgood, Ole Nielsen, Claus H Nielsen, Trevor Owens, Uffe Holmskov, Grith L Sørensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22509382/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22509382/?tool=EBI

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