Flow Cytometry Assessment of In Vitro Generated CD138+ Human Plasma Cells

The in vitro CD40-CD154 interaction promotes human B lymphocytes differentiation into plasma cells. Currently, CD138 is the hallmark marker enabling the detection of human plasma cells, both in vitro and in vivo; its presence can be monitored by flow cytometry using a specific antibody. We have deve...

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Bibliographic Details
Main Authors: Rayelle Itoua Maïga, Jennifer Lemieux, Annie Roy, Carl Simard, Sonia Néron
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/536482