Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain

<p>Abstract</p> <p>Background</p> <p>The Elk-1 transcription factor is a member of a group of proteins called ternary complex factors, which serve as a paradigm for gene regulation in response to extracellular signals. Its deregulation has been linked to multiple human...

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Bibliographic Details
Main Authors: Hussain Abrar, Shaw Peter E, Hirst Jonathan D
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Cheminformatics
Online Access:http://www.jcheminf.com/content/3/1/49