Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions

Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.

Bibliographic Details
Main Authors:	Sarah Rennie, Maria Dalby, Lucas van Duin, Robin Andersson
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-017-02798-1

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spelling	doaj-8fba3c63d1ce45de95bd48d281f5b53b2021-05-11T10:29:21ZengNature Publishing GroupNature Communications2041-17232018-02-019111610.1038/s41467-017-02798-1Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactionsSarah Rennie0Maria Dalby1Lucas van Duin2Robin Andersson3The Bioinformatics Centre, Department of Biology, University of CopenhagenThe Bioinformatics Centre, Department of Biology, University of CopenhagenThe Bioinformatics Centre, Department of Biology, University of CopenhagenThe Bioinformatics Centre, Department of Biology, University of CopenhagenTranscriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.https://doi.org/10.1038/s41467-017-02798-1
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson
spellingShingle	Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions Nature Communications
author_facet	Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson
author_sort	Sarah Rennie
title	Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
title_short	Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
title_full	Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
title_fullStr	Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
title_full_unstemmed	Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
title_sort	transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-02-01
description	Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.
url	https://doi.org/10.1038/s41467-017-02798-1
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Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions

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