Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions

Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.

Bibliographic Details
Main Authors: Sarah Rennie, Maria Dalby, Lucas van Duin, Robin Andersson
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02798-1