Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment.

Gastric cancer is associated with chronic inflammation and Helicobacter pylori infection. Th17 cells are CD4(+) T cells associated with infections and inflammation; but their role and mechanism of induction during carcinogenesis is not understood. Gastric myofibroblasts/fibroblasts (GMF) are abundan...

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Bibliographic Details
Main Authors: Irina V Pinchuk, Katherine T Morris, Robert A Nofchissey, Rachel B Earley, Jeng-Yih Wu, Thomas Y Ma, Ellen J Beswick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554710?pdf=render