Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells

Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells

Abstract Background The human genome is constantly exposed to numerous environmental genotoxicants. To prevent the detrimental consequences induced by the expansion of damaged cells, cellular protective systems such as nucleotide excision repair (NER) exist and serve as a primary pathway for repairi...

Full description

Bibliographic Details
Main Authors: Akira Sassa, Takayuki Fukuda, Akiko Ukai, Maki Nakamura, Michihito Takabe, Takeji Takamura-Enya, Masamitsu Honma, Manabu Yasui
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Genes and Environment
Subjects:
Nucleotide excision repair
XPC
CSB
Environmental mutagen
Cytotoxicity
TK6
Online Access:http://link.springer.com/article/10.1186/s41021-019-0130-y

Internet

http://link.springer.com/article/10.1186/s41021-019-0130-y

Similar Items