Deciphering Transcriptional Dynamics In Vivo by Counting Nascent RNA Molecules.

Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra and extracellular cues is one of the leading challenges in modern genomics. The development of novel single-cell sequencing and imaging techniques, as well as a better exploitation of currently availab...

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Bibliographic Details
Main Authors: Sandeep Choubey, Jane Kondev, Alvaro Sanchez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4636183?pdf=render