Deciphering Transcriptional Dynamics In Vivo by Counting Nascent RNA Molecules.
Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra and extracellular cues is one of the leading challenges in modern genomics. The development of novel single-cell sequencing and imaging techniques, as well as a better exploitation of currently availab...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4636183?pdf=render |