Adverse Outcomes in Obese Cardiac Surgery Patients Correlates With Altered Branched-Chain Amino Acid Catabolism in Adipose Tissue and Heart

Adverse Outcomes in Obese Cardiac Surgery Patients Correlates With Altered Branched-Chain Amino Acid Catabolism in Adipose Tissue and Heart

Background: Predicting relapses of post-operative complications in obese patients who undergo cardiac surgery is significantly complicated by persistent metabolic maladaptation associated with obesity. Despite studies supporting the linkages of increased systemic branched-chain amino acids (BCAAs) d...

Full description

Bibliographic Details
Main Authors: Dipsikha Biswas, Kathleen Tozer, Khoi T. Dao, Lester J. Perez, Angella Mercer, Amy Brown, Intekhab Hossain, Alexandra M. Yip, Christie Aguiar, Hany Motawea, Keith R. Brunt, Jennifer Shea, Jean F. Legare, Ansar Hassan, Petra C. Kienesberger, Thomas Pulinilkunnil
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Endocrinology
Subjects:
BCAA
BCKDH
BCAA metabolism
obesity
subcutaneous adipose
atrial appendage
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00534/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00534/full

Similar Items