Synthesis, NMR and Crystallographic Studies of 2-Substituted Dihydroquinazolinones Derived from (S)-Phenylethylamine

Synthesis, NMR and Crystallographic Studies of 2-Substituted Dihydroquinazolinones Derived from (S)-Phenylethylamine

2,3-Dihydro-3-[(S)-1-phenethyl]quinazolinone and some new 2-substitutedderivatives bearing isopropyl, o-nitrophenyl and p-nitrophenyl groups were prepared in40-90% yield by amidation of isatoic anhydride with (S)-phenylethylamine, followed bycondensation with triethyl orthoformate, isopropylaldehyde...

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Bibliographic Details
Main Authors: Cirilo García-Martínez, Jaime M. Priego, Patricia Flores, Claudia Ortíz-Nava, Jaime Escalante
Format: Article
Language:English
Published: MDPI AG 2007-02-01
Series:Molecules
Subjects:
Chiral dihydroquinazolinones
π-stacking interactions
NMR method
configurational analysis.
Online Access:http://www.mdpi.com/1420-3049/12/2/173/

Internet

http://www.mdpi.com/1420-3049/12/2/173/

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