Endocytosis of chikungunya virus into mammalian cells: role of clathrin and early endosomal compartments.

The replicative cycle of chikungunya virus (CHIKV), an alphavirus that recently re-emerged in India and in Indian Ocean area, remains mostly unknown. The aim of the present study was to investigate the intracellular trafficking pathway(s) hijacked by CHIKV to enter mammalian cells.Entry pathways wer...

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Bibliographic Details
Main Authors: Eric Bernard, Maxime Solignat, Bernard Gay, Nathalie Chazal, Stephen Higgs, Christian Devaux, Laurence Briant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2900206?pdf=render