Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior.

Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior.

Individuals with Cornelia de Lange Syndrome (CdLS) display diverse developmental deficits, including slow growth, multiple limb and organ abnormalities, and intellectual disabilities. Severely-affected individuals most often have dominant loss-of-function mutations in the Nipped-B-Like (NIPBL) gene,...

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Bibliographic Details
Main Authors: Yaning Wu, Maria Gause, Dongbin Xu, Ziva Misulovin, Cheri A Schaaf, Ramya C Mosarla, Elizabeth Mannino, Megan Shannon, Emily Jones, Mi Shi, Wen-Feng Chen, Olivia L Katz, Amita Sehgal, Thomas A Jongens, Ian D Krantz, Dale Dorsett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4636142?pdf=render

Internet

http://europepmc.org/articles/PMC4636142?pdf=render

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