The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

Symbiotic microbes impact the function and development of the central nervous system (CNS); however, little is known about the contribution of the microbiota during viral-induced neurologic damage. We identify that commensals aid in host defense following infection with a neurotropic virus through e...

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Bibliographic Details
Main Authors: D Garrett Brown, Raymond Soto, Soumya Yandamuri, Colleen Stone, Laura Dickey, Joao Carlos Gomes-Neto, Elissa D Pastuzyn, Rickesha Bell, Charisse Petersen, Kaitlin Buhrke, Robert S Fujinami, Ryan M O'Connell, W Zac Stephens, Jason D Shepherd, Thomas E Lane, June L Round
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-07-01
Series:eLife
Subjects:
microbiota
TLR 4
Neurological damage
microglia
JHMV
Online Access:https://elifesciences.org/articles/47117

Internet

https://elifesciences.org/articles/47117

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