Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

BACKGROUND: Ulcerative colitis (UC) is associated with differential colonic expression of genes involved in immune response (e.g. IL8) and barrier integrity (e.g. cadherins). MicroRNAs (miRNAs) are regulators of gene expression and are involved in various immune-related diseases. In this study, we i...

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Main Authors: Jan Van der Goten, Wiebe Vanhove, Katleen Lemaire, Leentje Van Lommel, Kathleen Machiels, Willem-Jan Wollants, Vicky De Preter, Gert De Hertogh, Marc Ferrante, Gert Van Assche, Paul Rutgeerts, Frans Schuit, Séverine Vermeire, Ingrid Arijs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4278881?pdf=render