Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D

During aging the immune system is dysregulated. Especially plasmacytoid dendritic cells (pDCs) and myeloid DCs (mDCs) have reduced Toll like receptor (TLR)-mediated responses resulting in increased susceptibility to infections. Consumption of bovine lactoferrin (bLF) has been shown to reduce infecti...

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Bibliographic Details
Main Authors: Marloes van Splunter, Olaf Perdijk, Henriëtte Fick-Brinkhof, Anouk L. Feitsma, Esther G. Floris-Vollenbroek, Ben Meijer, Sylvia Brugman, Huub F. J. Savelkoul, Els van Hoffen, R. J. Joost van Neerven
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
GOS
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02677/full