Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma

To investigate whether mutation profiling and microsatellite instability (MSI) status were associated with clinicopathological features and the prognosis in metastatic colorectal cancer (mCRC), mutations in RAS (including KRAS, NRAS, and HRAS) and BRAF were determined by Sanger sequencing. Tumor mis...

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Bibliographic Details
Main Authors: Jianhua Liu, Weiqiang Zeng, Chengzhi Huang, Junjiang Wang, Dongyang Yang, Dong Ma
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/4585802