Thioredoxin glutathione reductase as a novel drug target: evidence from Schistosoma japonicum.

BACKGROUND: Schistosomiasis remains a major public health concern affecting billions of people around the world. Currently, praziquantel is the only drug of choice for treatment of human schistosomiasis. The emergence of drug resistance to praziquantel in schistosomes makes the development of novel...

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Bibliographic Details
Main Authors: LiJun Song, JiaHuang Li, ShuYing Xie, ChunYan Qian, Jie Wang, Wei Zhang, Xuren Yin, ZiChun Hua, ChuanXin Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285170?pdf=render