Photodynamic therapy inhibits p-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a

<p>Abstract</p> <p>Background</p> <p>Multidrug resistance (MDR) is frequently observed after prolonged treatment in human hepatoma with conventional anti-tumor drugs, and photodynamic therapy (PDT) is a recently suggested alternative to overcome MDR. The therapeutic pot...

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Bibliographic Details
Main Authors: Kong Siu-Kai, Waye Mary, Tsui Stephen, Xuan Ngoc-Ha, Zhang Dong-Mei, Tang Patrick, Fong Wing-Ping, Fung Kwok-Pui
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/56