Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells

Paclitaxel is a microtubule stabilizing drug that causes dividing cells to arrest and then undergo apoptosis. It also has antiangiogenic activity because it alters cytoskeletal structure, affecting migration and invasion. Paclitaxel is an effective treatment for AIDS-related Kaposi’s sarcoma (KS). K...

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Bibliographic Details
Main Authors: Jie Cai, Tong Zheng, Rizwan Masood, D. Lynne Smith, David R. Hinton, Caryn Nae Kim, Guofu Fang, Kapil Bhalla, Parkash S. Gill
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/S1357714X00000074