Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway

Background: integrins have been associated with the development of chemotherapy resistant tumour cells, mostly those of hematopoietic origin, by mediating the binding to the extracellular matrix. The relevance for solid tumour cells and the underlying mechanisms remain elusive. Methods: using MTT as...

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Bibliographic Details
Main Authors: Maria B. R. Piva, Bastian Jakubzig, Gerd Bendas
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/9/9/125