Monitoring circulating gammadelta T cells in cancer patients to optimize gammadelta T cell-based immunotherapy

Monitoring circulating gammadelta T cells in cancer patients to optimize gammadelta T cell-based immunotherapy

The success of gammadelta (gd) T cell-based immunotherapy, where the cytotoxic activity of circulating gd T lymphocytes is activated by nitrogen-containing bisphosphonates (n-BP), or possibly by bispecific antibodies or the combination of both, requires a profound knowledge of patients´ gd T cells....

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Bibliographic Details
Main Authors: Hans-Heinrich eOberg, Christian eKellner, Matthias ePeipp, Susanne eSebens, Sabine eAdam-Klages, Martin eGramatzki, Dieter eKabelitz, Daniela eWesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Immunology
Subjects:
human
Monitoring
Pancreatic Ductal Adenocarcinoma
Gamma Delta T cells
Phosphoantigen
bispecific antibodies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00643/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00643/full

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