Androgen-Independent Prostate Cancer: Potential Role of Androgen and ErbB Receptor Signal Transduction Crosstalk

Androgen-Independent Prostate Cancer: Potential Role of Androgen and ErbB Receptor Signal Transduction Crosstalk

In prostate cancer (PC), increasing evidence suggests that androgen receptor (AR) signalling is functional under conditions of maximal androgen blockade. PC cells survive and proliferate in the altered hormonal environment possibly by interactions between growth factor-activated pathways and AR sig...

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Bibliographic Details
Main Authors: Soha Salama El Sheikh, Jan Domin, Paul Abel, Gordon Stamp, El-Nasir Lalani
Format: Article
Language:English
Published: Elsevier 2003-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
androgen receptor
ErbB receptors
MAPK
prostate cancer
AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558603800015

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http://www.sciencedirect.com/science/article/pii/S1476558603800015

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