Fluorescent Protein Inserts in between NC and SP2 Are Tolerated for Assembly, Release and Maturation of HIV with Limited Infectivity

We report the design of a fluorescent HIV construct that is labeled by insertion of fluorescent protein between the nucleocapsid (NC) and spacer peptide 2 (SP2) domains of Gag and further show that the fluorescent protein is released from its confines within Gag during maturation. This fluorescent H...

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Bibliographic Details
Main Authors: Mourad Bendjennat, Saveez Saffarian
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/11/973