The Downstream Regulation of Chemokine Receptor Signalling: Implications for Atherosclerosis
Heterotrimeric G-protein-coupled receptors (GPCRs) are key mediators of intracellular signalling, control numerous physiological processes, and are one of the largest class of proteins to be pharmacologically targeted. Chemokine-induced macrophage recruitment into the vascular wall is an early patho...
Main Authors: | Jyoti Patel, Keith M. Channon, Eileen McNeill |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2013/459520 |
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