IVIg immune reconstitution treatment alleviates the state of persistent immune activation and suppressed CD4 T cell counts in CVID.

Common variable immunodeficiency (CVID) is characterized by defective B cell function, impaired antibody production, and increased susceptibility to bacterial infections. Here, we addressed the hypothesis that poor antibody-mediated immune control of infections may result in substantial perturbation...

Full description

Bibliographic Details
Main Authors: Dominic Paquin-Proulx, Bianca A N Santos, Karina I Carvalho, Myrthes Toledo-Barros, Ana Karolina Barreto de Oliveira, Cristina M Kokron, Jorge Kalil, Markus Moll, Esper G Kallas, Johan K Sandberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793979?pdf=render