A metabolomic study of rats with doxorubicin-induced cardiomyopathy and Shengmai injection treatment.

Doxorubicin-induced cardiomyopathy (DOX-CM) is a severe complication of doxorubicin (DOX) chemotherapy. Characterized by cumulative and irreversible myocardial damage, its pathogenesis has not been fully elucidated. Shengmai Injection (SMI), a Traditional Chinese Medicine, may alleviate myocardial i...

Full description

Bibliographic Details
Main Authors: Yu Chen, Yong Tang, Ya-Chen Zhang, Xiao-Hong Huang, Yu-Quan Xie, Yin Xiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4418690?pdf=render