Yeast IME2 functions early in meiosis upstream of cell cycle-regulated SBF and MBF targets.

In Saccharomyces cerevisiae, the G1 cyclin/cyclin-dependent kinase (CDK) complexes Cln1,-2,-3/Cdk1 promote S phase entry during the mitotic cell cycle but do not function during meiosis. It has been proposed that the meiosis-specific protein kinase Ime2, which is required for normal timing of pre-me...

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Bibliographic Details
Main Authors: George S Brush, Nicole A Najor, Alan A Dombkowski, Daniela Cukovic, Kara E Sawarynski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290606?pdf=render