Fused Deposition Modeling (FDM) 3D Printed Tablets for Intragastric Floating Delivery of Domperidone

Abstract The aim of this study was to explore the feasibility of fused deposition modeling (FDM) 3D printing to prepare intragastric floating sustained release (FSR) tablets. Domperidone (DOM), an insoluble weak base, was chosen as a model drug to investigate the potential of FSR in increasing its o...

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Bibliographic Details
Main Authors: Xuyu Chai, Hongyu Chai, Xiaoyu Wang, Jingjing Yang, Jin Li, Yan Zhao, Weimin Cai, Tao Tao, Xiaoqiang Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03097-x