Genetic and Functional Characterization of Toll-Like Receptor Responses in Immunocompetent Patients With CMV Mononucleosis

Genetic and Functional Characterization of Toll-Like Receptor Responses in Immunocompetent Patients With CMV Mononucleosis

Background: Human cytomegalovirus (CMV) modulates both innate and adaptive immune responses. However, limited data are available on the role of receptors of innate immunity, such as toll-like receptors (TLRs) in contributing to antiviral responses and inflammation.Objectives: The aim of this transla...

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Bibliographic Details
Main Authors: Giada Frascaroli, Giada Rossini, Virginia Maltoni, Michele Bartoletti, Patrizia Ortolani, Sara Gredmark-Russ, Francesco Gelsomino, Alessandra Moroni, Silvia Silenzi, Gastone Castellani, Vittorio Sambri, Antonio Mastroianni, Wolfram Brune, Stefania Varani
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cytomegalovirus
mononucleosis
toll-like receptors
polymorphism
pro-inflammatory cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00386/full

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https://www.frontiersin.org/article/10.3389/fcimb.2020.00386/full

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