Identification of novel DNA hypermethylation of the adenylate kinase 5 promoter in colorectal adenocarcinoma

Abstract Adenylate kinase 5 (AK5) belongs to the adenylate kinase family that catalyses reversible phosphate transfer between adenine nucleotides, and it is related to various energetic signalling mechanisms. However, the role of AK5 in colorectal cancer (CRC) has not been reported. In this study, A...

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Bibliographic Details
Main Authors: Bokyung Ahn, Yang Seok Chae, Soo Kyung Lee, Moa Kim, Hyeon Soo Kim, Ji Wook Moon, Sun-Hwa Park
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92147-6