Leveraging hierarchical population structure in discrete association studies.

Population structure can confound the identification of correlations in biological data. Such confounding has been recognized in multiple biological disciplines, resulting in a disparate collection of proposed solutions. We examine several methods that correct for confounding on discrete data with h...

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Bibliographic Details
Main Authors: Jonathan Carlson, Carl Kadie, Simon Mallal, David Heckerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1899226?pdf=render