Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation.

Kinases play fundamental roles in the brain. Through complex signaling pathways, kinases regulate the strength of protein:protein interactions (PPI) influencing cell cycle, signal transduction, and electrical activity of neurons. Changes induced by kinases on neuronal excitability, synaptic plastici...

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Bibliographic Details
Main Authors: Wei-Chun Hsu, Miroslav N Nenov, Alexander Shavkunov, Neli Panova, Ming Zhan, Fernanda Laezza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319734?pdf=render