TNF-alpha and insulin-resistance: metabolic effects of in vivo therapeutic blockade
Insulin resistance is a key pathophysiologic feature of obesity, type 2 diabetes mellitus and prediabetic states (impaired fasting glucose, impaired glucose tolerance). TNF-α, a proinflammatory cytokine, plays an important role in the pathogenesis of insulin resistance associated with inflammation d...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2011-06-01
|
| Series: | Reumatismo |
| Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/449 |